Hello Ladies, For those of you that read my request last week trying to understand what DHEA does for fertility. I did a ton of research and what I found out is nothing sort of unbelievable. So I did more poking around the web and this is what I found out. First you should know I am in what is called Poor Ovarian Reserve or Ovarian Failure so I am a bit obsessed with finding ways to improve my ovarian reserve and increase my egg product and quality (For the record the Docs think this is caused by my weight loss. 110 pounds three years ago. – go figure!). :grr: I read this article and then Googled it (DHEA Supplement Could Help Women on Fertility Treatment - EmpowHER.com). I also went to the Fertility Forums and asked if anyone was prescribed DHEA or had been using it with positive results. - The answer was a strong yes. I looked further in the research study and this is what I found: - Patients took 75mg a day of Micronized DHEA (1 25mg pill per meal.) It must be micronized. - Taking it with a meal that has a whole vegetable or vegetable oil increased absorption by binding to the veg oil. - Original research studies concluded after 2 months showed little to no (major) improvement of fertility only slight improvement. - The research study in this article and studies/patient accounts after this study showed women that took DHEA as prescribed above for at least FOUR months showed a threefold chance of carrying a healthy pregnancy to term. - The women in the study were age 35 - 45 with FSH of 15 - 20. All women got pregnant and all but one of the women carried to term (19 healthy pregnancies) - For the fertility treatment to work you must take the DHEA with a Gondotropin (as did all the women in the research studies) A Gandotropin is something like Gonal-F or Follistim - DHEA has also been shown to dramatically improve sperm count, health and motility for men. End of the day I started taking Natures Plus DHEA about a week ago. I will post periodically on here with my test results. (Is anyone interested in doing our own research study?? It would be VERY VERY interesting to know how others fare taking DHEA.) The pills are small white capsules and I've had no stomach or other complications. I got mine at Vitamin Shoppe. The Natures Plus has Bioperine which helps with absorption. Natures Plus: http://www.naturesplus.com/products/productDetail.asp?criteria=search&searchVar=4968&productnumber=4968&category=29 OH! I was really focused on finding a DHEA that was vegan and pharmaceutical grade that had a certification from an independent lab. When I opened the Natures Plus it had a certificate of authentication stating pharmaceutical grade DHEA. – yay. What ever ones you get make sure they are Micronized and I read that taking the ones labled "Yam" or "Soy" based do not work and that many pills do not have DHEA in them. (See my links and research below) Be sure to read this link about a 43 year old that went from producting 3 egg to 18 after 8 cycles: http://www.centerforhumanreprod.com/pdf/dheafs.pdf I don’t know if it will be a miracle cure. But I’m hoping with taking the Royal Jelly pills, DHEA and all the other stuff I’m doing something magical will happen… soon! :cheer: Merry Christmas, Eileen Micronization: http://en.wikipedia.org/wiki/MicronizationDHEA National Institute of Health: DHEA: MedlinePlus Supplements Wikipedia: Dehydroepiandrosterone - Wikipedia, the free encyclopedia Poor Ovarian Reserve: Poor ovarian reserve - Wikipedia, the free encyclopedia Quote: DHEA: Recent clinical trial by the Center for Human Reproduction in New York showed significant effectiveness. Leonidas and Eudoxia Mamas report six cases of premature ovarian failure. After two to six months of treatment with DHEA (Two 25 mg capsules daily in five cases and three 25 mg capsules daily in one case.) all women conceived. One delivered via C-section, one aborted at 7 weeks and the remaining four were reported at 11 to 27 weeks gestation. Ages were from 37 to 40. FSH levels were from 30 to 112 mIU/mL. Ammenorhea ranged from 9 to 13 months. In addition, there is strong evidence that continuous micronized DHEA 25 mg TID reduces miscarriage and aneuploidy rates, especially above age 35. Source: 1 - Barad, David and Gleicher, Norbert, 2006. "Effect of dehydroepiandrosterone on oocyte and embryo yields, embryo grade and cell number in IVF. Human Reproduction, 21(11):2845-2849. PMID: 16997936. 2 - (This is a MUST read) http://www.centerforhumanreprod.com/pdf/dheafs.pdf 3 - Barad DH, Gleicher N., 2005. "Increased oocyte production. Premature Ovarian Failure: Premature ovarian failure - Wikipedia, the free encyclopedia Quote: Over the last five years a Greek research team has successfully implemented the use of dehydroepiandrosterone (DHEA) for the fertility treatment of women suffering with POF. The majority of the patients were referred for donor eggs or surrogacy, however after a few months of DHEA administration they succeeded in getting pregnant through IVF, IUI, IUTPI or natural conception. Until now a great number of babies have been born after treatment with DHEA. Source: Mamas L, Mamas E. 2009. "Premature ovarian failure and dehydroepiandrosterone." Fertil Steril., 91(2):644-6.